Učitavanje...
Enhanced expression of β cell Ca(V)3.1 channels impairs insulin release and glucose homeostasis
Voltage-gated calcium 3.1 (Ca(V)3.1) channels are absent in healthy mouse β cells and mediate minor T-type Ca(2+) currents in healthy rat and human β cells but become evident under diabetic conditions. Whether more active Ca(V)3.1 channels affect insulin secretion and glucose homeostasis remains eni...
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| Izdano u: | Proc Natl Acad Sci U S A |
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| Glavni autori: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2020
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6955371/ https://ncbi.nlm.nih.gov/pubmed/31871187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1908691117 |
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