B2 and ALU retrotransposons are self-cleaving ribozymes whose activity is enhanced by EZH2

Transposable elements make up half of the mammalian genome. One of the most abundant is the short interspersed nuclear element (SINE). Among their million copies, B2 accounts for ∼350,000 in the mouse genome and has garnered special interest because of emerging roles in epigenetic regulation. Our re...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Hernandez, Alfredo J., Zovoilis, Athanasios, Cifuentes-Rojas, Catherine, Han, Lu, Bujisic, Bojan, Lee, Jeannie T.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2020
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6955291/
https://ncbi.nlm.nih.gov/pubmed/31871160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1917190117
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