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Destabilization of B2 RNA by EZH2 activates the stress response
More than 98% of the mammalian genome is noncoding and interspersed transposable elements account for ~50% of noncoding space. Here, we demonstrate that a specific interaction between the Polycomb protein, EZH2, and RNA made from B2 SINE retrotransposons controls stress-responsive genes in mouse cel...
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| Publié dans: | Cell |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5552366/ https://ncbi.nlm.nih.gov/pubmed/27984727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.11.041 |
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