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Cross-Reactive CD8 T-Cell Responses Elicited by Adenovirus Type 5-Based HIV-1 Vaccines Contributed to Early Viral Evolution in Vaccine Recipients Who Became Infected

Because of HIV’s vast sequence diversity, the ability of the CD8 T-cell response to recognize several variants of a single epitope is an important consideration for vaccine design. Cross-recognition of viral epitopes by CD8 T cells is associated with viral control during HIV-1 infection, but little...

詳細記述

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書誌詳細
出版年:J Virol
主要な著者: Boppana, Sushma, Fiore-Gartland, Andrew, Bansal, Anju, Goepfert, Paul
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6955250/
https://ncbi.nlm.nih.gov/pubmed/31645444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01632-19
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