BNC1 regulates cell heterogeneity in human pluripotent stem cell-derived epicardium

The murine developing epicardium heterogeneously expresses the transcription factors TCF21 and WT1. Here, we show that this cell heterogeneity is conserved in human epicardium, regulated by BNC1 and associated with cell fate and function. Single cell RNA sequencing of epicardium derived from human p...

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Dades bibliogràfiques
Publicat a:Development
Autors principals: Gambardella, Laure, McManus, Sophie A., Moignard, Victoria, Sebukhan, Derya, Delaune, Agathe, Andrews, Simon, Bernard, William G., Morrison, Maura A., Riley, Paul R., Göttgens, Berthold, Gambardella Le Novère, Nicolas, Sinha, Sanjay
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2019
Matèries:
Human Development
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6955213/
https://ncbi.nlm.nih.gov/pubmed/31767620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.174441
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