BNC1 regulates cell heterogeneity in human pluripotent stem cell-derived epicardium

The murine developing epicardium heterogeneously expresses the transcription factors TCF21 and WT1. Here, we show that this cell heterogeneity is conserved in human epicardium, regulated by BNC1 and associated with cell fate and function. Single cell RNA sequencing of epicardium derived from human p...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Gambardella, Laure, McManus, Sophie A., Moignard, Victoria, Sebukhan, Derya, Delaune, Agathe, Andrews, Simon, Bernard, William G., Morrison, Maura A., Riley, Paul R., Göttgens, Berthold, Gambardella Le Novère, Nicolas, Sinha, Sanjay
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2019
Assuntos:
Human Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6955213/
https://ncbi.nlm.nih.gov/pubmed/31767620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.174441
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