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Determining Physical Mechanisms of Gene Expression Regulation from Single Cell Gene Expression Data

Many genes are expressed in bursts, which can contribute to cell-to-cell heterogeneity. It is now possible to measure this heterogeneity with high throughput single cell gene expression assays (single cell qPCR and RNA-seq). These experimental approaches generate gene expression distributions which...

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Detaylı Bibliyografya
Yayımlandı:PLoS Comput Biol
Asıl Yazarlar: Ezer, Daphne, Moignard, Victoria, Göttgens, Berthold, Adryan, Boris
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995004/
https://ncbi.nlm.nih.gov/pubmed/27551778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005072
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