The Paf1 complex and P-TEFb have reciprocal and antagonist roles in maintaining multipotent neural crest progenitors

Multipotent progenitor populations are necessary for generating diverse tissue types during embryogenesis. We show the RNA polymerase-associated factor 1 complex (Paf1C) is required to maintain multipotent progenitors of the neural crest (NC) lineage in zebrafish. Mutations affecting each Paf1C comp...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Jurynec, Michael J., Bai, Xiaoying, Bisgrove, Brent W., Jackson, Haley, Nechiporuk, Alex, Palu, Rebecca A. S., Grunwald, Hannah A., Su, Yi-Chu, Hoshijima, Kazuyuki, Yost, H. Joseph, Zon, Leonard I., Grunwald, David Jonah
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2019
Assuntos:
Stem Cells and Regeneration
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6955205/
https://ncbi.nlm.nih.gov/pubmed/31784460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.180133
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