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DUETT quantitatively identifies known and novel events in nascent RNA structural dynamics from chemical probing data

MOTIVATION: RNA molecules can undergo complex structural dynamics, especially during transcription, which influence their biological functions. Recently developed high-throughput chemical probing experiments that study RNA cotranscriptional folding generate nucleotide-resolution ‘reactivities’ for e...

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Publicat a:Bioinformatics
Autors principals: Xue, Albert Y, Yu, Angela M, Lucks, Julius B, Bagheri, Neda
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954663/
https://ncbi.nlm.nih.gov/pubmed/31389563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz449
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