Downregulation of MYPT1 increases tumor resistance in ovarian cancer by targeting the Hippo pathway and increasing the stemness

BACKGROUND: Ovarian cancer is one of the most common and malignant cancers, partly due to its late diagnosis and high recurrence. Chemotherapy resistance has been linked to poor prognosis and is believed to be linked to the cancer stem cell (CSC) pool. Therefore, elucidating the molecular mechanisms...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Mol Cancer
Autors principals: Muñoz-Galván, Sandra, Felipe-Abrio, Blanca, Verdugo-Sivianes, Eva M., Perez, Marco, Jiménez-García, Manuel P., Suarez-Martinez, Elisa, Estevez-Garcia, Purificacion, Carnero, Amancio
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954568/
https://ncbi.nlm.nih.gov/pubmed/31926547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-020-1130-z
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars