New markers for human ovarian cancer that link platinum resistance to the cancer stem cell phenotype and define new therapeutic combinations and diagnostic tools

BACKGROUND: Ovarian cancer is the leading cause of gynecologic cancer-related death, due in part to a late diagnosis and a high rate of recurrence. Primary and acquired platinum resistance is related to a low response probability to subsequent lines of treatment and to a poor survival. Therefore, a...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Muñoz-Galván, Sandra, Felipe-Abrio, Blanca, García-Carrasco, Miguel, Domínguez-Piñol, Julia, Suarez-Martinez, Elisa, Verdugo-Sivianes, Eva M., Espinosa-Sánchez, Asunción, Navas, Lola E., Otero-Albiol, Daniel, Marin, Juan J., Jiménez-García, Manuel P., García-Heredia, Jose M., Quiroga, Adoración G., Estevez-Garcia, Purificacion, Carnero, Amancio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547556/
https://ncbi.nlm.nih.gov/pubmed/31159852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1245-5
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