A microRNA signature of toxic extrasynaptic N-methyl-D-aspartate (NMDA) receptor signaling

The cellular consequences of N-Methyl-D-Aspartate receptor (NMDAR) stimulation depend on the receptors’ subcellular localization. Synaptic NMDARs promote plasticity and survival whereas extrasynaptic NMDARs mediate excitotoxicity and contribute to cell death in neurodegenerative diseases. The mechan...

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Udgivet i:Mol Brain
Main Authors: Bas-Orth, Carlos, Koch, Mirja, Lau, David, Buchthal, Bettina, Bading, Hilmar
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954508/
https://ncbi.nlm.nih.gov/pubmed/31924235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-020-0546-0
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