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TFregulomeR reveals transcription factors’ context-specific features and functions

Transcription factors (TFs) are sequence-specific DNA binding proteins, fine-tuning spatiotemporal gene expression. Since genomic occupancy of a TF is highly dynamic, it is crucial to study TF binding sites (TFBSs) in a cell-specific context. To date, thousands of ChIP-seq datasets have portrayed th...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Lin, Quy Xiao Xuan, Thieffry, Denis, Jha, Sudhakar, Benoukraf, Touati
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954419/
https://ncbi.nlm.nih.gov/pubmed/31754708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz1088
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