Conditional deletion of E11/Podoplanin in bone protects against ovariectomy-induced increases in osteoclast formation and activity

E11/Podoplanin (Pdpn) is implicated in early osteocytogenesis and the formation of osteocyte dendrites. This dendritic network is critical for bone modelling/remodelling, through the production of receptor activator of nuclear factor κ B (RANK)-ligand (RANKL). Despite this, the role of Pdpn in the c...

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Dades bibliogràfiques
Publicat a:Biosci Rep
Autors principals: Staines, Katherine A., Hopkinson, Mark, Dillon, Scott, Stephen, Louise A., Fleming, Robert, Sophocleous, Antonia, Buttle, David J., Pitsillides, Andrew A., Farquharson, Colin
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2020
Matèries:
Aging
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954370/
https://ncbi.nlm.nih.gov/pubmed/31894854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20190329
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