Conditional deletion of E11/podoplanin in bone protects against load-induced osteoarthritis

BACKGROUND: Subchondral bone (SCB) thickening is one of the earliest detectable changes in osteoarthritic joints and is considered a potential trigger for subsequent articular cartilage degeneration. In this manuscript, we examine whether disruption to the SCB osteocyte network contributes to the in...

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Detalhes bibliográficos
Publicado no:BMC Musculoskelet Disord
Main Authors: Staines, Katherine A., Ikpegbu, Ekele, Törnqvist, Anna E., Dillon, Scott, Javaheri, Behzad, Amin, Anish K., Clements, Dylan N., Buttle, David J., Pitsillides, Andrew A., Farquharson, Colin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6661085/
https://ncbi.nlm.nih.gov/pubmed/31351471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12891-019-2731-9
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