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E11/Podoplanin Protein Stabilization Through Inhibition of the Proteasome Promotes Osteocyte Differentiation in Murine in Vitro Models

The transmembrane glycoprotein E11 is considered critical in early osteoblast–osteocyte transitions (osteocytogenesis), however its function and regulatory mechanisms are still unknown. Using the late osteoblast MLO‐A5 cell line we reveal increased E11 protein/mRNA expression (P < 0.001) concomit...

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Detalhes bibliográficos
Publicado no:J Cell Physiol
Main Authors: Staines, Katherine A., Prideaux, Matt, Allen, Steve, Buttle, David J., Pitsillides, Andrew A., Farquharson, Colin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832367/
https://ncbi.nlm.nih.gov/pubmed/26639105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.25282
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