E11/Podoplanin Protein Stabilization Through Inhibition of the Proteasome Promotes Osteocyte Differentiation in Murine in Vitro Models

The transmembrane glycoprotein E11 is considered critical in early osteoblast–osteocyte transitions (osteocytogenesis), however its function and regulatory mechanisms are still unknown. Using the late osteoblast MLO‐A5 cell line we reveal increased E11 protein/mRNA expression (P < 0.001) concomit...

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Publicat a:J Cell Physiol
Autors principals: Staines, Katherine A., Prideaux, Matt, Allen, Steve, Buttle, David J., Pitsillides, Andrew A., Farquharson, Colin
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2015
Matèries:
Original Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832367/
https://ncbi.nlm.nih.gov/pubmed/26639105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.25282
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