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E11/Podoplanin Protein Stabilization Through Inhibition of the Proteasome Promotes Osteocyte Differentiation in Murine in Vitro Models

The transmembrane glycoprotein E11 is considered critical in early osteoblast–osteocyte transitions (osteocytogenesis), however its function and regulatory mechanisms are still unknown. Using the late osteoblast MLO‐A5 cell line we reveal increased E11 protein/mRNA expression (P < 0.001) concomit...

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Physiol
Hauptverfasser: Staines, Katherine A., Prideaux, Matt, Allen, Steve, Buttle, David J., Pitsillides, Andrew A., Farquharson, Colin
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832367/
https://ncbi.nlm.nih.gov/pubmed/26639105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.25282
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