Germline polymorphisms in the Von Hippel-Lindau and Hypoxia-inducible factor 1-alpha genes, gene-environment and gene-gene interactions and renal cell cancer

We investigated the relationship between germline single nucleotide polymorphisms (SNPs) in Von Hippel-Lindau (VHL) and Hypoxia-inducible factor 1-alpha (HIF1A), and their gene-environment and gene-gene interactions, and clear-cell RCC (ccRCC) risk. Furthermore, we assessed the relationship between...

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Publicado no:Sci Rep
Main Authors: van de Pol, Jeroen A. A., van den Brandt, Piet A., van Engeland, Manon, Godschalk, Roger W. L., van Schooten, Frederik-Jan, Hogervorst, Janneke G. F., Schouten, Leo J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954183/
https://ncbi.nlm.nih.gov/pubmed/31924838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56980-0
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