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Deep2Full: Evaluating strategies for selecting the minimal mutational experiments for optimal computational predictions of deep mutational scan outcomes

Performing a complete deep mutational scan with all single point mutations may not be practical, and may not even be required, especially if predictive computational models can be developed. Computational models are however naive to cellular response in the myriads of assay-conditions. In a realisti...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Sruthi, C. K., Prakash, Meher
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954071/
https://ncbi.nlm.nih.gov/pubmed/31923916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0227621
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