Engineering the interactions between a plant‐produced HIV antibody and human Fc receptors

Plants can provide a cost‐effective and scalable technology for production of therapeutic monoclonal antibodies, with the potential for precise engineering of glycosylation. Glycan structures in the antibody Fc region influence binding properties to Fc receptors, which opens opportunities for modula...

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Detalhes bibliográficos
Publicado no:Plant Biotechnol J
Main Authors: Stelter, Szymon, Paul, Mathew J., Teh, Audrey Y.‐H., Grandits, Melanie, Altmann, Friedrich, Vanier, Jessica, Bardor, Muriel, Castilho, Alexandra, Allen, Rachel Louise, Ma, Julian K‐C.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6953194/
https://ncbi.nlm.nih.gov/pubmed/31301102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pbi.13207
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