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Bayesian differential analysis of gene regulatory networks exploiting genetic perturbations

BACKGROUND: Gene regulatory networks (GRNs) can be inferred from both gene expression data and genetic perturbations. Under different conditions, the gene data of the same gene set may be different from each other, which results in different GRNs. Detecting structural difference between GRNs under d...

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Détails bibliographiques
Publié dans:BMC Bioinformatics
Auteurs principaux: Li, Yan, Liu, Dayou, Li, Tengfei, Zhu, Yungang
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6953167/
https://ncbi.nlm.nih.gov/pubmed/31918656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-3314-3
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