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Endoplasmic Reticulum Protein Disulfide Isomerase Shapes T Cell Efficacy for Adoptive Cellular Therapy of Tumors

Effective cancer therapies simultaneously restrict tumor cell growth and improve anti-tumor immune responses. Targeting redox-dependent protein folding enzymes within the endoplasmic reticulum (ER) is an alternative approach to activation of the unfolded protein response (UPR) and a novel therapeuti...

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Publicado en:Cells
Autores principales: Hurst, Katie E., Lawrence, Kiley A., Reyes Angeles, Lety, Ye, Zhiwei, Zhang, Jie, Townsend, Danyelle M., Dolloff, Nathan, Thaxton, Jessica E.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6953024/
https://ncbi.nlm.nih.gov/pubmed/31779147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8121514
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