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Endoplasmic Reticulum Stress Contributes to Mitochondrial Exhaustion of CD8(+) T cells
Tumor antigen-specific T cells rapidly lose energy and effector function in tumors. The cellular mechanisms by which energy loss and inhibition of effector function occur in tumor infiltrating lymphocytes (TILs) are ill-defined, and methods to identify tumor-antigen-specific TILs that experience suc...
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| Publicado no: | Cancer Immunol Res |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6397687/ https://ncbi.nlm.nih.gov/pubmed/30659052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-18-0182 |
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