Tristetraprolin/ZFP36 Regulates the Turnover of Autoimmune-Associated HLA-DQ mRNAs

HLA class II genes encode highly polymorphic heterodimeric proteins functioning to present antigens to T cells and stimulate a specific immune response. Many HLA genes are strongly associated with autoimmune diseases as they stimulate self-antigen specific CD4(+) T cells driving pathogenic responses...

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Publicado en:Cells
Main Authors: Pisapia, Laura, Hamilton, Russell S., Farina, Federica, D’Agostino, Vito, Barba, Pasquale, Strazzullo, Maria, Provenzani, Alessandro, Gianfrani, Carmen, Del Pozzo, Giovanna
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6953012/
https://ncbi.nlm.nih.gov/pubmed/31817224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8121570
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