HLA-DQA1 and HLA-DQB1 Alleles, Conferring Susceptibility to Celiac Disease and Type 1 Diabetes, Are More Expressed Than Non-Predisposing Alleles and Are Coordinately Regulated

HLA DQA1*05 and DQB1*02 alleles encoding the DQ2.5 molecule and HLA DQA1*03 and DQB1*03 alleles encoding DQ8 molecules are strongly associated with celiac disease (CD) and type 1 diabetes (T1D), two common autoimmune diseases (AD). We previously demonstrated that DQ2.5 genes showed a higher expressi...

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Publicat a:Cells
Autors principals: Farina, Federica, Picascia, Stefania, Pisapia, Laura, Barba, Pasquale, Vitale, Serena, Franzese, Adriana, Mozzillo, Enza, Gianfrani, Carmen, Del Pozzo G, Giovanna
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6678473/
https://ncbi.nlm.nih.gov/pubmed/31331105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8070751
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