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Co-regulated expression of alpha and beta mRNAs encoding HLA-DR surface heterodimers is mediated by the MHCII RNA operon

Major histocompatibility complex class II (MHCII) molecules are heterodimeric surface proteins involved in the presentation of exogenous antigens during the adaptive immune response. We demonstrate the existence of a fine level of regulation, coupling the transcription and processing of mRNAs encodi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pisapia, Laura, Cicatiello, Valeria, Barba, Pasquale, Malanga, Donatella, Maffei, Antonella, Hamilton, Russell S., Del Pozzo, Giovanna
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2013
Schlagworte:
RNA
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616700/
https://ncbi.nlm.nih.gov/pubmed/23393186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt059
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