Contrasting effects of IFNα on MHC class II expression in professional vs. nonprofessional APCs: Role of CIITA type IV promoter

We previously demonstrated that, in ex vivo cultures, IFNα downregulates the expression of MHC class II (MHCII) genes in human non-professional APCs associated with pancreatic islets. IFNα has an opposing effect on MHCII expression in professional APCs. In this study, we found that the mechanism res...

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Detalhes bibliográficos
Main Authors: Pisapia, Laura, Pozzo, Giovanna Del, Barba, Pasquale, Citro, Alessandra, Harris, Paul E., Maffei, Antonella
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3862382/
https://ncbi.nlm.nih.gov/pubmed/24371581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.rinim.2012.09.001
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