NLRP3 Inflammasome and Mineralocorticoid Receptors Are Associated with Vascular Dysfunction in Type 2 Diabetes Mellitus

Aldosterone excess aggravates endothelial dysfunction in diabetes and hypertension by promoting the increased generation of reactive oxygen species, inflammation, and insulin resistance. Aldosterone activates the molecular platform inflammasome in immune system cells and contributes to vascular dysf...

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Publicado en:Cells
Autores principales: Ferreira, Nathanne Santos, Bruder-Nascimento, Thiago, Pereira, Camila André, Zanotto, Camila Zillioto, Prado, Douglas Silva, Silva, Josiane Fernandes, Rassi, Diane Meyre, Foss-Freitas, Maria Cristina, Alves-Filho, Jose Carlos, Carlos, Daniela, Tostes, Rita de Cássia
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6952964/
https://ncbi.nlm.nih.gov/pubmed/31817997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8121595
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