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The inflammasome NLRP3 plays a dual role on mouse corpora cavernosa relaxation

NLRP3 plays a role in vascular diseases. Corpora cavernosa (CC) is an extension of the vasculature. We hypothesize that NLRP3 plays a deleterious role in CC relaxation. Male C57BL/6 (WT) and NLRP3 deficient (NLRP3(−/−)) mice were used. Intracavernosal pressure (ICP/MAP) measurement was performed. Fu...

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Vydáno v:Sci Rep
Hlavní autoři: Fais, Rafael S., Rodrigues, Fernanda L., Pereira, Camila A., Mendes, Allan C., Mestriner, Fabíola, Tostes, Rita C., Carneiro, Fernando S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6838322/
https://ncbi.nlm.nih.gov/pubmed/31700106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52831-0
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