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A Membrane Permeable Prodrug of S223 for Selective Epac2 Activation in Living Cells
Signalling by cyclic adenosine monophosphate (cAMP) occurs via various effector proteins, notably protein kinase A and the guanine nucleotide exchange factors Epac1 and Epac2. These proteins are activated by cAMP binding to conserved cyclic nucleotide binding domains. The specific roles of the effec...
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| Publicado no: | Cells |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6952820/ https://ncbi.nlm.nih.gov/pubmed/31817822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8121589 |
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