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A Membrane Permeable Prodrug of S223 for Selective Epac2 Activation in Living Cells

Signalling by cyclic adenosine monophosphate (cAMP) occurs via various effector proteins, notably protein kinase A and the guanine nucleotide exchange factors Epac1 and Epac2. These proteins are activated by cAMP binding to conserved cyclic nucleotide binding domains. The specific roles of the effec...

詳細記述

保存先:
書誌詳細
出版年:Cells
主要な著者: Xu, Yunjian, Schwede, Frank, Wienk, Hans, Tengholm, Anders, Rehmann, Holger
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6952820/
https://ncbi.nlm.nih.gov/pubmed/31817822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8121589
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