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‘Trim’ming PolyQ proteins with engineered PML

Protein abnormalities are the major cause of neurodegenerative diseases such as SCA (Spinocerebellar Ataxia). Protein misfolding and impaired degradation leads to the build-up of protein aggregates inside the cell, which may further cause cellular degeneration. Reducing levels of either the soluble...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Biotechnol Bioeng
मुख्य लेखकों: Dhar, Neha, Arsiwala, Ammar, Murali, Shruthi, Kane, Ravi S.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6952540/
https://ncbi.nlm.nih.gov/pubmed/31710088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.27220
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