Leveraging allelic imbalance to refine fine-mapping for eQTL studies

Many disease risk loci identified in genome-wide association studies are present in non-coding regions of the genome. Previous studies have found enrichment of expression quantitative trait loci (eQTLs) in disease risk loci, indicating that identifying causal variants for gene expression is importan...

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Bibliografske podrobnosti
izdano v:PLoS Genet
Main Authors: Zou, Jennifer, Hormozdiari, Farhad, Jew, Brandon, Castel, Stephane E., Lappalainen, Tuuli, Ernst, Jason, Sul, Jae Hoon, Eskin, Eleazar
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2019
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6952111/
https://ncbi.nlm.nih.gov/pubmed/31834882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008481
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