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The thiocyanate analog selenocyanate is a more potent antimicrobial pro-drug that also is selectively detoxified by the host
A hallmark of cystic fibrosis (CF) lung pathology is an increased susceptibility to pulmonary infections. Thiocyanate ((−)SCN) is an endogenous component of the innate immunity’s peroxidase system that converts (−)SCN to the antimicrobial agent hypothiocyanite (HOSCN). We have previously shown that...
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| 出版年: | Free Radic Biol Med |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6951815/ https://ncbi.nlm.nih.gov/pubmed/31740228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2019.11.016 |
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