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Biochemical Mechanisms and Therapeutic Potential of the Pseudohalide Thiocyanate in Human Health

Thiocyanate (SCN(−)) is an ubiquitous molecule in mammalian biology, reaching up to mM concentrations in extracellular fluids. Two-electron oxidation of SCN(−) by H(2)O(2) produces hypothiocyanous acid (HOSCN), a potent antimicrobial species. This reaction is catalyzed by chordate peroxidases (e.g.,...

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Detalhes bibliográficos
Publicado no:Free Radic Res
Principais autores: Chandler, Joshua D., Day, Brian J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959427/
https://ncbi.nlm.nih.gov/pubmed/25564094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10715762.2014.1003372
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