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Biochemical Mechanisms and Therapeutic Potential of the Pseudohalide Thiocyanate in Human Health
Thiocyanate (SCN(−)) is an ubiquitous molecule in mammalian biology, reaching up to mM concentrations in extracellular fluids. Two-electron oxidation of SCN(−) by H(2)O(2) produces hypothiocyanous acid (HOSCN), a potent antimicrobial species. This reaction is catalyzed by chordate peroxidases (e.g.,...
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| Udgivet i: | Free Radic Res |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4959427/ https://ncbi.nlm.nih.gov/pubmed/25564094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10715762.2014.1003372 |
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