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THIOCYANATE: A potentially useful therapeutic agent with host defense and antioxidant properties

Thiocyanate (SCN) functions in host defense as part of the secreted lactoperoxidase (LPO) microbicidal pathway. SCN is the preferred substrate for LPO-driven catalytic reduction of hydrogen peroxide (H(2)O(2)) forming hypothiocyanous acid (HOSCN). HOSCN is selectively generated by many peroxidase en...

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Detalhes bibliográficos
Main Authors: Chandler, Joshua D., Day, Brian J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983948/
https://ncbi.nlm.nih.gov/pubmed/22968041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2012.07.029
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