Defective Inflammatory Monocyte Development in IRF8-Deficient Mice Abrogates Migration to the West Nile Virus-Infected Brain

IRF8 (interferon-regulatory factor-8) plays a critical role in regulating myeloid cell differentiation. However, the role of this transcription factor in the development of Ly6C+ inflammatory monocytes and their migration to the infected brain has not been examined. We have previously shown that Wes...

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Veröffentlicht in:J Innate Immun
Hauptverfasser: Terry, Rachael L., Deffrasnes, Celine, Getts, Daniel R., Minten, Carsten, van Vreden, Caryn, Ashhurst, Thomas M., Getts, Meghann T., Xie, Rui Dan Vicki, Campbell, Iain L., King, Nicholas J.C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: S. Karger AG 2014
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6951104/
https://ncbi.nlm.nih.gov/pubmed/25277331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000365972
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