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Recruiting RyRs to Open in a Ca(2+) Release Unit: Single-RyR Gating Properties Make RyR Group Dynamics
In cardiac myocytes, clusters of type-2 ryanodine receptors (RyR2s) release Ca(2+) from the sarcoplasmic reticulum (SR) via a positive feedback mechanism in which fluxed Ca(2+) activates nearby RyRs. Although the general principles of this are understood, less is known about how single-RyR gating pr...
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| 出版年: | Biophys J |
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| 第一著者: | |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Biophysical Society
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6950848/ https://ncbi.nlm.nih.gov/pubmed/31839264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.11.021 |
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