An in silico exploration of combining Interleukin-12 with Oxaliplatin to treat liver-metastatic colorectal cancer

BACKGROUND: Combining anti-cancer therapies with orthogonal modes of action, such as direct cytotoxicity and immunostimulatory, hold promise for expanding clinical benefit to patients with metastatic disease. For instance, a chemotherapy agent Oxaliplatin (OXP) in combination with Interleukin-12 (IL...

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Bibliografiske detaljer
Udgivet i:BMC Cancer
Main Authors: Wang, Qing, Wang, Zhijun, Wu, Yan, Klinke, David J.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6950805/
https://ncbi.nlm.nih.gov/pubmed/31914948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-6500-9
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