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Tumor necrosis factor α-induced protein 1 as a novel tumor suppressor through selective downregulation of CSNK2B blocks nuclear factor-κB activation in hepatocellular carcinoma

BACKGROUND: Tumor necrosis factor α-induced protein 1 (TNFAIP1) is frequently downregulated in cancer cell lines and promotes cancer cell apoptosis. However, its role, clinical significance and molecular mechanisms in hepatocellular carcinoma (HCC) are unknown. METHODS: The expression of TNFAIP1 in...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Xiao, Ye, Huang, Shulan, Qiu, Feng, Ding, Xiaofeng, Sun, Yi, Wei, Chenxi, Hu, Xiang, Wei, Ke, Long, Shengwen, Xie, Lina, Xun, Yu, Chen, Wen, Zhang, Zhijian, Liu, Ning, Xiang, Shuanglin
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6950786/
https://ncbi.nlm.nih.gov/pubmed/31901862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.102603
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