A Natural Quinazoline Derivative from Marine Sponge Hyrtios erectus Induces Apoptosis of Breast Cancer Cells via ROS Production and Intrinsic or Extrinsic Apoptosis Pathways

Here, we report the therapeutic potential of a natural quinazoline derivative (2-chloro-6-phenyl-8H-quinazolino[4,3-b]quinazolin-8-one) isolated from marine sponge Hyrtios erectus against human breast cancer. The cytotoxicity of the compound was investigated on a human breast carcinoma cell line (MC...

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Detaylı Bibliyografya
Yayımlandı:Mar Drugs
Asıl Yazarlar: De, Arun Kumar, Muthiyan, Ramachandran, Mondal, Samiran, Mahanta, Nilkamal, Bhattacharya, Debasis, Ponraj, Perumal, Muniswamy, Kangayan, Kundu, Anandamoy, Kundu, Madhu Sudhan, Sunder, Jai, Karunakaran, Dhanasekar, Bera, Asit Kumar, Roy, Sibnarayan Dam, Malakar, Dhruba
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6950652/
https://ncbi.nlm.nih.gov/pubmed/31771152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md17120658
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