Evidence That Calebin A, a Component of Curcuma Longa Suppresses NF-κB Mediated Proliferation, Invasion and Metastasis of Human Colorectal Cancer Induced by TNF-β (Lymphotoxin)

Objective: Natural polyphenol Calebin A has been recently discovered as a novel derivate from turmeric with anti-cancer potential. Pro-inflammatory cytokine TNF-β (lymphotoxin α) is a stimulant for cancer cell malignity via activation of NF-κB pathway, also in colorectal cancer (CRC). Here, we inves...

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Veröffentlicht in:Nutrients
Hauptverfasser: Buhrmann, Constanze, Popper, Bastian, Kunnumakkara, Ajaikumar B., Aggarwal, Bharat B., Shakibaei, Mehdi
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6950382/
https://ncbi.nlm.nih.gov/pubmed/31805741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu11122904
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