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Single Spheroid Metabolomics: Optimizing Sample Preparation of Three-Dimensional Multicellular Tumor Spheroids

Tumor spheroids are important model systems due to the capability of capturing in vivo tumor complexity. In this work, the experimental design of metabolomics workflows using three-dimensional multicellular tumor spheroid (3D MTS) models is addressed. Non-scaffold based cultures of the HCT116 colon...

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Vydáno v:Metabolites
Hlavní autoři: Rusz, Mate, Rampler, Evelyn, Keppler, Bernhard K., Jakupec, Michael A., Koellensperger, Gunda
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6950217/
https://ncbi.nlm.nih.gov/pubmed/31847430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo9120304
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