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Multicellular spheroids: a three-dimensional in vitro culture system to study tumour biology

The growth of tumour cells as three-dimensional multicellular spheroids in vitro has led to important insights in tumour biology, since properties of the in vivo-tumour such as proliferation or nutrient gradients, can be studied under controlled conditions. While this review starts with an update of...

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Detalhes bibliográficos
Main Authors: KUNZ-SCHUGHART, LEONI A., KREUTZ, MARINA, KNUECHEL, RUTH
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219428/
https://ncbi.nlm.nih.gov/pubmed/9614346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2613.1998.00051.x
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