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Single Spheroid Metabolomics: Optimizing Sample Preparation of Three-Dimensional Multicellular Tumor Spheroids

Tumor spheroids are important model systems due to the capability of capturing in vivo tumor complexity. In this work, the experimental design of metabolomics workflows using three-dimensional multicellular tumor spheroid (3D MTS) models is addressed. Non-scaffold based cultures of the HCT116 colon...

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Detalhes bibliográficos
Publicado no:Metabolites
Main Authors: Rusz, Mate, Rampler, Evelyn, Keppler, Bernhard K., Jakupec, Michael A., Koellensperger, Gunda
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6950217/
https://ncbi.nlm.nih.gov/pubmed/31847430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo9120304
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