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Critical Analysis of Neuronal Cell and the Mouse Bioassay for Detection of Botulinum Neurotoxins

Botulinum Neurotoxins (BoNTs) are a large protein family that includes the most potent neurotoxins known to humankind. BoNTs delivered locally in humans at low doses are widely used pharmaceuticals. Reliable and quantitative detection of BoNTs is of paramount importance for the clinical diagnosis of...

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Bibliographic Details
Published in:Toxins (Basel)
Main Authors: Pellett, Sabine, Tepp, William H., Johnson, Eric A.
Format: Artigo
Language:Inglês
Published: MDPI 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6950160/
https://ncbi.nlm.nih.gov/pubmed/31817843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins11120713
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