Genome Mining of Marine-Derived Streptomyces sp. SCSIO 40010 Leads to Cytotoxic New Polycyclic Tetramate Macrolactams

Polycyclic tetramate macrolactams (PTMs) biosynthetic gene cluster are widely distributed in different bacterial types, especially in Streptomyces species. The mining of the genomic data of marine-derived Streptomyces sp. SCSIO 40010 reveals the presence of a putative PTM-encoding biosynthetic gene...

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Publicat a:Mar Drugs
Autors principals: Liu, Wei, Zhang, Wenjun, Jin, Hongbo, Zhang, Qingbo, Chen, Yuchan, Jiang, Xiaodong, Zhang, Guangtao, Zhang, Liping, Zhang, Weimin, She, Zhigang, Zhang, Changsheng
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6950151/
https://ncbi.nlm.nih.gov/pubmed/31775228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md17120663
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