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Targeted discovery of polycyclic tetramate macrolactams from an environmental Streptomyces strain

[Image: see text] A targeted PCR-based screening approach was used to identify candidate polycyclic tetramate macrolactam (PTM) biosynthetic gene clusters in environmental Streptomyces isolates. Isolation and characterization of the small molecules produced by one of the strains confirmed the produc...

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Autors principals: Cao, Shugeng, Blodgett, Joshua A. V., Clardy, Jon
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952660/
https://ncbi.nlm.nih.gov/pubmed/20843016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol1020064
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