Blockade of IGF2R improves muscle regeneration and ameliorates Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) is a debilitating fatal X‐linked muscle disorder. Recent findings indicate that IGFs play a central role in skeletal muscle regeneration and development. Among IGFs, insulinlike growth factor 2 (IGF2) is a key regulator of cell growth, survival, migration and differ...

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Publicat a:EMBO Mol Med
Autors principals: Bella, Pamela, Farini, Andrea, Banfi, Stefania, Parolini, Daniele, Tonna, Noemi, Meregalli, Mirella, Belicchi, Marzia, Erratico, Silvia, D'Ursi, Pasqualina, Bianco, Fabio, Legato, Mariella, Ruocco, Chiara, Sitzia, Clementina, Sangiorgi, Simone, Villa, Chiara, D'Antona, Giuseppe, Milanesi, Luciano, Nisoli, Enzo, Mauri, PierLuigi, Torrente, Yvan
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6949491/
https://ncbi.nlm.nih.gov/pubmed/31793167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201911019
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