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Blockade of IGF2R improves muscle regeneration and ameliorates Duchenne muscular dystrophy
Duchenne muscular dystrophy (DMD) is a debilitating fatal X‐linked muscle disorder. Recent findings indicate that IGFs play a central role in skeletal muscle regeneration and development. Among IGFs, insulinlike growth factor 2 (IGF2) is a key regulator of cell growth, survival, migration and differ...
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| 發表在: | EMBO Mol Med |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
John Wiley and Sons Inc.
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6949491/ https://ncbi.nlm.nih.gov/pubmed/31793167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201911019 |
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