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VPS35 regulates tau phosphorylation and neuropathology in tauopathy
The vacuolar protein sorting 35 (VPS35) is a major component of the retromer recognition core complex which regulates intracellular protein sorting and trafficking. Deficiency in VPS35 by altering APP/Aβ metabolism has been linked to late-onset Alzheimer’s disease. Here we report that VPS35 is signi...
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| Pubblicato in: | Mol Psychiatry |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6949432/ https://ncbi.nlm.nih.gov/pubmed/31289348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-019-0453-x |
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